Biotin and derivatives
IBA LifeSciences Biotin powder; 2 g
Biotin is a water-soluble B-complex vitamin, also known as vitamin B7 or vitamin H. It binds to the biotin-binding pockets of streptavidin, Strep-Tactin, and Strep-TactinXT with different affinities. As a result, it allows the efficient elution of Strep-tagII or Twin-Strep-tag fusion proteins from Strep-TactinXT, while maintaining the reusability of the resin. It can be used for preparation of Strep-TactinXT elution buffer, Buffer BXT. In addition, biotin can be used for elution of biotinylated proteins from Strep-Tactin, where it binds irreversibly to the resin. Hence, Strep-Tactin cannot be regenerated in this kind of application.
Medchemexpress LLC Biotin hydrazide | 66640-86-6 | MFCD00078532 | 98.7% | 258.34 g/mol | C10H18N4O2S | 1 G
Biotin hydrazide is a carbonyl-reactive biotinylation reagent that forms hydrazone linkages with oxidized carbohydrates and other carbonyl groups. It is used to introduce a biotin tag for detection, affinity capture, and enrichment of labeled proteins and glycoconjugates in biochemical assays and proteomics workflows.
- Reacts selectively with aldehydes and ketones after oxidation.
- Enables streptavidin-based detection and affinity purification.
- Suitable for labeling glycoproteins following periodate oxidation.
- Supplied as a solid reagent for solution preparation and storage.
- High purity for reproducible analytical and preparative work.
TARGETMOL CHEMICALS INC Cy3 NHS ester 5MG
Also available in 1 mg, 10 mg, 25 mg, 50 mg, 100 mg and bulk. Please contact Fisher for quotes. Cy3 NHS ester is a fluorescent dye used to label amino groups in proteins, peptides, antibodies, and oligonucleotides. The excitation/emission (Ex/Em) values of Cy3 NHS ester are 550 nm/570 nm. Purity 98.03%
Medchemexpress LLC Ibrutinib-biotin | 1599432-18-4 | MFCD30496724 | 99.7% | 1097.37 | C56H80N12O9S | 25 MG
Ibrutinib-biotin is a biotinylated probe in which the BTK inhibitor ibrutinib is linked to biotin via a long-chain linker (derived from patent WO2014059368A1 Compound 1-5). It is intended for research use to study Bruton's tyrosine kinase (BTK) binding, target engagement, and affinity-based assays.
- Biotinylated probe for affinity capture and target engagement studies.
- High potency against BTK with IC50 of 0.755-1.02 nM.
- High purity (99.66%) suitable for biochemical and cellular assays.
- Available in small quantities for assay development (25 mg).
- Includes downloadable datasheet, COA, and SDS for experimental reproducibility.
Medchemexpress LLC Cyanine5.5 NHS ester tetrafluoroborate | 2375105-86-3 | 98.4% | 767.66 | 50 MG
Cyanine5.5 NHS ester tetrafluoroborate is a common fluorescent marker that belongs to the cyanine dye series. It is designed to interact with biomolecules and can bind to double-helical DNA through intercalation, leading to enhanced fluorescence upon binding.
- Functions as a common fluorescent marker for biomolecules
- Interacts with various biomolecules
- Binds to double-helical DNA through intercalation
- Enhances fluorescence upon DNA binding
- Belongs to the cyanine dye series
Apexbio Technology LLC Sulfo-NHS-LC-D-Desthiobiotin 5X1mg
Sulfo-NHS-LC-D-Desthiobiotin is a sulfonated amine-reactive labeling reagent targeting primary amines on proteins or peptides It is designed to covalently label cell-surface proteins by reacting with lysine residues or protein N-termini thereby enabling selective modification of these proteins Sulfo-NHS-LC-D-Desthiobiotin exerts its biological activity primarily through covalent reaction with primary amines via its activated Sulfo-NHS ester Due to its membrane-impermeable negatively charged sulfonate group it selectively labels cell-surface proteins without entering intact cells Based on these chemical properties Sulfo-NHS-LC-D-Desthiobiotin holds research potential in affinity purification biotin-streptavidin interaction assays selective enrichment and analytical workflows involving reversible labeling of surface proteins
Medchemexpress LLC L-biotin (unnatural enantiomer of biotin) | 21788-37-4 | MFCD22373639 | 99.5% | 244.31 g·mol⁻¹ | C10H16N2O3S | 1 ML
L-biotin is the unnatural enantiomer of biotin supplied as a research reagent. It binds streptavidin in vitro and is provided as a ready-to-use 10 mM solution in DMSO (1 mL) or as solid powder in multiple pack sizes. Recommended storage conditions are -20°C for powder, and -80°C for stock solutions (up to 6 months).
- Unnatural enantiomer of biotin
- Binds streptavidin in vitro
- Available as 10 mM DMSO solution or solid powder
- High purity (>99%)
- Soluble in DMSO at high concentration
- Powder storage: -20°C; stock solution storage: -80°C (6 months)
Medchemexpress LLC L-biotin | 21788-37-4 | 99.7% | 244.31 g/mol | C10H16N2O3S | 10 MG
L-biotin is the unnatural enantiomer of biotin provided as a research-grade chemical standard for stereochemical studies and analytical applications. It is supplied with a certificate of analysis and a safety data sheet to support safe handling and quality verification.
- high reported purity suitable for analytical use
- available in small milligram pack sizes for research
- comes with COA and SDS documentation
- chemical formula C10H16N2O3S and molecular weight 244.31 g/mol
- intended for research use only; not for human use
Medchemexpress LLC Biotin hydrazide | 66640-86-6 | MFCD00078532 | 258.34 g/mol | C10H18N4O2S | 1 ML
Biotin hydrazide is a carbonyl-reactive biotinylation reagent used to label oxidized glycans, glycoproteins, and other carbonyl-containing biomolecules. It is supplied as a solid or as a 10 mM solution in DMSO for use in conjugation, detection, and enrichment workflows.
- Reacts with carbonyl groups to form stable hydrazone linkages.
- Supplied as solid or as a 10 mM solution in DMSO for convenience.
- Enables biotin-based detection and affinity purification workflows.
- Soluble in DMSO and moderately soluble in water, with solubility data provided.
- Stable when stored under recommended temperatures for long-term use.